Stress can hinder fertility and make it more challenging to conceive. The effects of stress on hormonal balance, menstrual health, ovary and sperm health, lifestyle, and well-being are significant. Managing stress and anxiety is an essential consideration when attempting conception. Research indicates that couples reporting positive feelings have higher pregnancy rates compared to those reporting tension and anxiety. Similarly, women experiencing higher stress levels have lower success rates with IVF than those with lower stress levels. Older patients, facing lower probability due to diminished egg reserves, may resist the advice of one specialist advocating the use of donor eggs. Instead, they may seek a specialist promising that age is not an impediment, potentially delaying more promising treatment and increasing stress levels. Another impact of infertility treatment stress can be withdrawal from sources of support. Feelings of guilt, shame, and regret can be stressful, leaving individuals sad and avoiding potential support. Fortunately, mental health professionals in reproductive medicine recognize stress’s impact on infertility and its treatment. They, along with others, have developed tools for individuals experiencing stress. Reducing stress during infertility treatment can have wide-ranging benefi ts, improving overall wellbeing and a sense of control.