Understanding premature ovarian failure - conceiveindiaivf

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Primary ovarian insufficiency, previously known as premature ovarian failure, is a condition that affects women well before they would typically reach menopause. A healthy woman’s ovaries produce estrogen, a hormone that regulates menstrual periods and fertility. However, as women age, their ovaries naturally cease estrogen production. In some cases, ovaries may stop functioning long before the expected onset of menopause (usually around the age of 51). If you are under 40, experiencing a cessation of egg production, and your menstrual periods have stopped, it may be indicative of primary ovarian insufficiency.

Causes

Within the ovaries are small sacs called follicles, which hold eggs as they mature. Girls are typically born with around 2 million eggs, which develop into these follicles and last until menopause. In primary ovarian insufficiency, follicles either deplete or malfunction, potentially influenced by genetic factors such as autoimmune disorders, chemotherapy, radiation therapy, genetic disorders like Fragile X syndrome and Turner syndrome, or viral infections. The likelihood of this condition may increase if there is a family history, especially if your mother or sister had it.

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Dr. Madhuri Roy

Dr. Madhuri Roy graduated as an MD in Obstetrics and Gynaecology in 2001 and completed her fellowship in Minimal access surgery (FMAS) from World Laproscopy Hospital. She is trained in Reproductive Medicine and endocrinology from prestigious Charles’s University of Czech Republic and is recognized by European society of Human Reproduction and Endocrinology (ESHREE) and European board of College of Obstretrics and Gynaecology (EBCOG).

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